This is also my understanding from my reading. Vyndamax and vyndaqel are the same drug in different forms. Regarding the other issue, wild type is a type of Attr.

Gary

From Pfizers website:

Both Vyndaqel and Vyndamax contain the same active ingredient called tafamidis. The difference between Vyndaqel and Vyndamax lies in the form of tafamidis they contain.

Vyndaqel contains the micronized meglumine salt of tafamidis, while Vyndamax contains the free acid form of tafamidis. Vyndamax was developed for patient convenience and this formulation allows patients to take just one capsule once per day. Patients taking Vyndaqel, on the other hand, need to take four capsules once a day.

Vyndaqel and Vyndamax are so similar that Pfizer was able to gain US Food and Drug Administration (FDA) approval for Vyndamax using its clinical trial data for Vyndaqel. Treatment with Vyndaqel or Vyndamax is intended to reduce death and hospitalization due to heart problems in people with ATTR-CM.

https://www.vyndamax.com/vyndaqel

In a study, VYNDAMAX 61 mg was shown to work the same way as VYNDAQEL 80 mg.

In US it’s either VYNDAMAX 61 mg 1 x or VYNDAQEL 20 mg 4 x

In Italy only vindaquel has been approved. The dose is one pill x day (61mg of Tafamidis).

Thanks Robert .. I emailed her.