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Biopsy. With it showing up in urine, does that mean it's affecting my kidneys?

September 17, 2025
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MyAmyloidosisTeam

When protein (like light chains) appears in urine, it can indicate kidney involvement in amyloidosis. This condition, called nephrotic syndrome, occurs when the kidneys aren't filtering properly due to amyloid deposits. However, a definitive diagnosis of kidney involvement typically requires additional testing.

Common signs Show Full Answer

When protein (like light chains) appears in urine, it can indicate kidney involvement in amyloidosis. This condition, called nephrotic syndrome, occurs when the kidneys aren't filtering properly due to amyloid deposits. However, a definitive diagnosis of kidney involvement typically requires additional testing.

Common signs of kidney involvement include:
• High levels of protein in urine
• Low blood protein levels
• High levels of fats and cholesterol in blood
• Swelling in legs, feet, or ankles To confirm whether your kidneys are affected, your healthcare provider may need to perform additional blood tests to check kidney function or possibly recommend a kidney biopsy. It's important to discuss these test results with your healthcare team to understand their full significance and determine if further testing is needed.

September 17, 2025

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