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Real members of MyAmyloidosisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Shortness of breath

A MyAmyloidosisTeam Member asked a question 💭
Orange nsw Australia

I had my first round of chemo three days ago iv noticed being short of breath bit shaky is this normal

October 10, 2025
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MyAmyloidosisTeam

Yes, shortness of breath can be a common experience after starting chemotherapy treatment for amyloidosis. This happens because amyloid proteins can affect your heart's ability to pump blood efficiently, which impacts oxygen circulation throughout your body.

Some key symptoms to be aware of
• Shortness of breath, even with Show Full Answer

Yes, shortness of breath can be a common experience after starting chemotherapy treatment for amyloidosis. This happens because amyloid proteins can affect your heart's ability to pump blood efficiently, which impacts oxygen circulation throughout your body.

Some key symptoms to be aware of:
• Shortness of breath, even with minimal activity
• Feeling shaky or dizzy
• Fatigue or extreme tiredness
• Difficulty lying flat on your back While these symptoms are common, it's important to communicate any new or concerning symptoms with your healthcare team. They can evaluate whether your symptoms are expected side effects of treatment or if they need to adjust your treatment plan.

Keep track of when you experience shortness of breath and what activities trigger it. This information will be helpful for your doctor to assess your condition properly.

October 10, 2025
A MyAmyloidosisTeam Member

Daratumumab is a monoclonal antibody medication used to treat multiple myeloma and other types of cancer. Common side effects of daratumumab include:
Common (occurring in more than 1 in 10 patients):
Infusion reactions (e.g., fever, chills, nausea, vomiting)
Back pain
Fatigue
Upper respiratory tract infections
Muscle spasms
Diarrhea
Constipation
Less common (occurring in 1 in 10 to 1 in 100 patients):
Allergic reactions (e.g., hives, swelling, difficulty breathing)
Low blood cell counts (white blood cells, red blood cells, platelets)
Nerve damage (e.g., numbness, tingling, weakness)
Joint pain
Headache
Dizziness
Blurred vision -

October 10, 2025
A MyAmyloidosisTeam Member

Did you receive daratumumab? Some people have allergic reactions to that drug with the first dose. Reactions were more prominent when the drug was given by IV as opposed to the dara FastPro shots. If it continues, do contact your doctors on Monday.

October 10, 2025

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