Where does systemic edema come from in amyloidosis?
Systemic edema (swelling throughout the body) in amyloidosis typically comes from heart or kidney involvement. When amyloid deposits build up in the heart, it can't pump blood effectively, leading to fluid retention. When kidneys are affected, they may leak protein and Show Full Answer
Where does systemic edema come from in amyloidosis?
Systemic edema (swelling throughout the body) in amyloidosis typically comes from heart or kidney involvement. When amyloid deposits build up in the heart, it can't pump blood effectively, leading to fluid retention. When kidneys are affected, they may leak protein and struggle to regulate fluid balance, also causing swelling.
Regarding GI nerve contribution to bloating:
You're right to think about nerve involvement! When amyloidosis affects the autonomic nerves that control digestion, it can slow down how your stomach and intestines move food through. This nerve damage can cause:
- Bloating
- Feeling full quickly
- Constipation or diarrhea
- Excess gas
This happens because the damaged nerves can't properly coordinate the muscle contractions needed for normal digestion, leading to delayed stomach emptying and intestinal movement.
About facial swelling:
Facial swelling in amyloidosis usually isn't from the same nerve mechanism as abdominal bloating. It's more commonly related to fluid retention from heart or kidney problems, or sometimes from direct amyloid deposits in facial tissues.
It's worth discussing both your abdominal bloating and any facial swelling with your amyloidosis specialist, as they can evaluate whether these symptoms are related to nerve involvement, organ function, or direct amyloid deposits.
March 11
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