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April 4
Can ATTR-CM amyloidosis cause stomach pain and digestive problems even when taking Vyndamax and Onpattro or Amvuttra?
Yes, amyloidosis can cause stomach pain and digestive problems even while on treatment. These symptoms happen because amyloid buildup can damage the nerves that control digestion, which are part of your Show Full Answer
Can ATTR-CM amyloidosis cause stomach pain and digestive problems even when taking Vyndamax and Onpattro or Amvuttra?
Yes, amyloidosis can cause stomach pain and digestive problems even while on treatment. These symptoms happen because amyloid buildup can damage the nerves that control digestion, which are part of your autonomic nervous system.
Common digestive symptoms in ATTR amyloidosis include:
* Nausea and vomiting
* Constipation
* Diarrhea
* Abdominal pain
* Unintentional weight loss
* Feeling full too quickly
* Reflux or GERD
While medications like Onpattro and Amvuttra work to slow disease progression by reducing abnormal protein buildup, they don't immediately reverse existing nerve damage. Some people do see improvement in digestive symptoms over time with treatment, as one MyAmyloidosisTeam member shared: "I have been on treatment for two months, and the diarrhea caused by amyloidosis has completely disappeared."
If you're experiencing persistent or worsening digestive symptoms while on treatment, it's important to discuss this with your care team. They can help determine if these symptoms are related to your amyloidosis or if additional management strategies might help.
April 4
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