Which type of amyloidosis affects joints?
Joint pain is most commonly associated with AL amyloidosis (amyloid light-chain amyloidosis), also known as primary amyloidosis. This is the most common type of amyloidosis in many countries.
Dialysis-related amyloidosis can also cause joint problems. This type typically affects Show Full Answer
Which type of amyloidosis affects joints?
Joint pain is most commonly associated with AL amyloidosis (amyloid light-chain amyloidosis), also known as primary amyloidosis. This is the most common type of amyloidosis in many countries.
Dialysis-related amyloidosis can also cause joint problems. This type typically affects the joints, tendons, and bones in people who have been on long-term kidney dialysis.
Joint pain is not commonly seen with AA amyloidosis (secondary amyloidosis) or hereditary amyloidosis (familial amyloidosis).
When amyloidosis affects joints, abnormal amyloid proteins build up in the synovial membranes (the tissues that cushion and lubricate joints), cartilage, or tendons around the joints. This can cause:
* Joint stiffness
* Swelling in and around the joint
* Joint weakness
* Carpal tunnel syndrome
* "Shoulder pad" appearance (enlarged shoulders)
If you're experiencing joint pain along with other amyloidosis symptoms, it's important to discuss this with your doctor so they can determine the cause and best treatment approach.
April 14
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