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Left leg due to lack of blood flow and pain. Could this be caused by my amyloidosis? Now I am have on my right foot 2 toes that have sore spots along with nerve pain, which is how it started on my left leg. I am so frightened, is there anything I can do to slow/stop this before I lose my right leg?

April 27
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A MyAmyloidosisTeam Member

Shirley, Call your Doctor as soon as possible. You should not have to wait for the next appointment. I have tingling in both feet occasionally but I have never gone through what you have described with one leg. My prayers are with you as you travel this difficult time.

May 13
MyAmyloidosisTeam

First, it's completely understandable to feel frightened — what you're going through is incredibly difficult, and your concern for your right leg is valid and serious. Please contact your specialist or care team as soon as possible about the symptoms in your right foot. This is urgent.

Yes, what you're experiencing can be Show Full Answer

First, it's completely understandable to feel frightened — what you're going through is incredibly difficult, and your concern for your right leg is valid and serious. Please contact your specialist or care team as soon as possible about the symptoms in your right foot. This is urgent.

Yes, what you're experiencing can be connected to AA amyloidosis. Amyloid deposits can damage peripheral nerves — the nerves outside the brain and spinal cord — leading to nerve pain, sore spots, numbness, and reduced blood flow to the limbs. The nerve-related symptoms you're describing in your right foot — sore spots and nerve pain — are recognized signs of peripheral neuropathy in amyloidosis. These can include:

- Burning or stabbing pain
- Tingling or numbness
- Sensitivity in the skin
- Weakness in the feet and legs

The fact that these symptoms mirror how things started with your left leg makes it even more important to act quickly. Here are some steps worth discussing urgently with your medical team:

- Vascular assessment — Ask for an urgent referral to a vascular specialist to check blood flow in your right leg
- Podiatry care — A podiatrist can help monitor and protect your toes from worsening sores
- Neurology referral — To assess and manage the nerve pain
- Wound care — Even small sores need careful attention to prevent infection
- Occupational or physical therapy — Can help with mobility and protecting your remaining limb

Treating the underlying AA amyloidosis as aggressively as possible may also help slow further nerve and tissue damage. Your care team needs to know about these symptoms today — don't wait.

April 27
A MyAmyloidosisTeam Member

AL

May 8
A MyAmyloidosisTeam Member

Shirley, do you have AL, or AA?
Sorry you are going through this, it is very scary! Prayers!

April 28

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