In AL amyloidosis, the excess protein is made in the bone marrow — the soft, spongy tissue found inside certain bones.
Specifically, cells in the bone marrow called plasma cells (a type of white blood cell) malfunction and produce abnormal proteins known as light chains. These light chains then misfold and clump together Show Full Answer
In AL amyloidosis, the excess protein is made in the bone marrow — the soft, spongy tissue found inside certain bones.
Specifically, cells in the bone marrow called plasma cells (a type of white blood cell) malfunction and produce abnormal proteins known as light chains. These light chains then misfold and clump together, forming the amyloid deposits that build up in tissues and organs over time. It's worth noting that these proteins come entirely from within the body — they are not related to the protein you eat in food. So there's no need to cut protein from your diet unless your doctor specifically advises it due to kidney involvement.
June 29