This is a really important question, and the honest answer is: it's possible in some cases, but it's not guaranteed — and it largely depends on how well the underlying amyloidosis is treated.
The heart wall thickens because amyloid proteins build up in the tissue. If treatment successfully reduces the production of those Show Full Answer
This is a really important question, and the honest answer is: it's possible in some cases, but it's not guaranteed — and it largely depends on how well the underlying amyloidosis is treated.
The heart wall thickens because amyloid proteins build up in the tissue. If treatment successfully reduces the production of those proteins, the heart may have a chance to recover some function. A MyAmyloidosisTeam member shared an encouraging example — their LV wall thickness dropped from 16.5 to 12, and their ejection fraction improved from 46% to 57% after treatment. Their medical team described this as a remarkable improvement.
That said, heart damage from amyloidosis can sometimes be difficult to reverse, and in some cases may be permanent. Early detection and treatment give the best chance of improvement. Here's what can influence whether improvement is possible:
- Type of amyloidosis — AL and ATTR amyloidosis are treated differently, and outcomes vary
- How early treatment begins — earlier intervention generally leads to better results
- How well treatment controls amyloid production — reducing the source protein can slow or stop further damage
- Regular monitoring — echocardiograms and biomarker tests help track whether the heart is responding to treatment
Staying closely connected with a cardiology team experienced in amyloidosis is key to understanding your personal outlook.
July 15
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