While both conditions involve abnormal protein buildup called amyloid deposits, they affect different parts of the body. In systemic amyloidosis, the protein deposits typically form in organs like the kidneys, heart, liver, or other organs. In contrast, with Alzheimer's disease, the amyloid buildup occurs specifically in Show Full Answer
While both conditions involve abnormal protein buildup called amyloid deposits, they affect different parts of the body. In systemic amyloidosis, the protein deposits typically form in organs like the kidneys, heart, liver, or other organs. In contrast, with Alzheimer's disease, the amyloid buildup occurs specifically in the brain.
There is no clear evidence that systemic amyloidosis directly causes or leads to dementia or brain-related amyloid plaques. However, there is a specific condition called cerebral amyloid angiopathy (CAA) where amyloid can build up in the brain's blood vessels. This can potentially lead to:
• Bleeding in the brain
• Sudden confusion
• Stroke-like symptoms
• Problems with thinking and memory
If you're concerned about cognitive symptoms, it's important to discuss these with your healthcare provider for proper evaluation.
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Is There a Link Between Amyloidosis and Dementia?
September 10, 2025