Common skin symptoms of AL amyloidosis include:
• Bruising easily, particularly around the eyes
• Blood-filled blisters
• Petechiae (small red spots on skin)
• Ecchymoses (flat, bluish-purple spots)
• Patches of thickened, itchy skin
• Waxy bumps on eyelids, neck, groin, or anal areas
• Hair loss
• Jaundice (yellowing of Show Full Answer
Common skin symptoms of AL amyloidosis include:
• Bruising easily, particularly around the eyes
• Blood-filled blisters
• Petechiae (small red spots on skin)
• Ecchymoses (flat, bluish-purple spots)
• Patches of thickened, itchy skin
• Waxy bumps on eyelids, neck, groin, or anal areas
• Hair loss
• Jaundice (yellowing of skin/eyes)
• Brittle, crumbling nails There are also several specific forms of skin amyloidosis:
• Lichen amyloidosis - Causes itchy, scaly reddish-brown rash typically on feet, legs and arms
• Macular amyloidosis - Creates itchy, flat brown/gray spots usually on upper back and chest
• Nodular amyloidosis - Produces firm red, pink or brown bumps on face, limbs, torso or genitals
• Amyloidosis cutis dyschromia - Results in patches of lighter or darker skin
Early diagnosis and treatment is essential for managing these skin manifestations and improving quality of life.
September 13, 2025
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