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Real members of MyAmyloidosisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyAmyloidosisTeam Member asked a question 💭
WINNIPEG, Manitoba, Ca

I was diagnosed with a positive biopsy from a Carpal tunnel surgery. Another biopsy called Fat Pad came back negative. Is this common to have one biopsy come back positive and one negative? I understand that amyloid can affect a single organ. Thanks

September 24, 2025
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MyAmyloidosisTeam

Yes, it's possible to have different biopsy results since amyloidosis can affect specific organs or tissues while not being present in others. The only definitive way to diagnose amyloidosis is through biopsy, and doctors may need to take samples from different areas to confirm the diagnosis.

Carpal tunnel syndrome has Show Full Answer

Yes, it's possible to have different biopsy results since amyloidosis can affect specific organs or tissues while not being present in others. The only definitive way to diagnose amyloidosis is through biopsy, and doctors may need to take samples from different areas to confirm the diagnosis.

Carpal tunnel syndrome has been increasingly recognized as an early indicator of amyloidosis, particularly in certain types of the condition. Some MyAmyloidosisTeam members have shared similar experiences of being diagnosed through carpal tunnel biopsies. Your healthcare team might recommend additional testing to determine the specific type of amyloidosis you have and its extent. This could include:

• Blood and urine tests
• Imaging tests (ultrasound, MRI, CT scan)
• Additional biopsies of other potentially affected organs if needed

This comprehensive approach helps create the most appropriate treatment plan for your specific situation.

September 24, 2025

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