Connect with others who understand.

  • Learn from expert-reviewed resources
  • Real advice from people who’ve been there
  • People who understand what you’re going through
Sign Up Log In
Powered By
Real members of MyAmyloidosisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyAmyloidosisTeam Member asked a question 💭
October 9, 2025
 · 
Be the first to react
A MyAmyloidosisTeam Member

For some patients this question can boil down to the financial toxicity that can be caused by these expensive meds. For patients on Medicare, Attruby may be more cost effective for patients on traditional Medicare who also have a supplemental plan. Since Attruby must be administered by a medical professional it is covered by Medicare PART B. Depending on which supplemental plan a patient has, all of the costs of this drug may be covered by the combined insurances leaving you with no out of pocket expense at all. Vyndamax is an oral medication that is self administered, therefore it falls under PART D Medicare plans and leaves the patient owing a large copay. But the good news is, your annual Part D out of pocket maximum will probably be met after filling the Rx one time. There are financial assistance foundations that can help cover the copays, if you qualify financially and if the copay foundation has funds available when you need the assistance. Just some things for you and your doctor to consider when choosing your treatment.

October 15, 2025
MyAmyloidosisTeam

What are the key differences between Attruby (acoramidis) and Vyndamax (tafamidis) for treating cardiomyopathy in amyloidosis?

Both medications work by stabilizing the transthyretin protein to prevent harmful amyloid deposits, but they have different side effect profiles:

Attruby (approved in 2024)
• Common side effects Show Full Answer

What are the key differences between Attruby (acoramidis) and Vyndamax (tafamidis) for treating cardiomyopathy in amyloidosis?

Both medications work by stabilizing the transthyretin protein to prevent harmful amyloid deposits, but they have different side effect profiles:

Attruby (approved in 2024):
• Common side effects include diarrhea and mild stomach pain
• May cause temporary changes in kidney function that usually resolve

Vyndamax:
• May cause allergic reactions including:
• Trouble swallowing
• Hives or itchy skin rashes
• Chest tightness
• Fast heartbeat Both medications are FDA-approved treatment options for ATTR cardiomyopathy. The choice between them should be made in consultation with your healthcare provider, who can consider your specific medical history and circumstances to determine which medication might be most appropriate for you.

October 9, 2025

Related Questions

View All