ATTR-wt (wild-type) amyloidosis can cause weight loss through several mechanisms related to how the condition affects multiple body systems. The buildup of abnormal TTR proteins can impact:
• Digestive function and autonomic nerves that control digestion
• Appetite regulation
• Nutrient absorption
• Overall metabolism Show Full Answer
ATTR-wt (wild-type) amyloidosis can cause weight loss through several mechanisms related to how the condition affects multiple body systems. The buildup of abnormal TTR proteins can impact:
• Digestive function and autonomic nerves that control digestion
• Appetite regulation
• Nutrient absorption
• Overall metabolism Common digestive symptoms that may contribute to weight loss include:
• Loss of appetite
• Frequent vomiting
• Upset stomach
• Constipation or diarrhea
• Digestive system blockages
If you're experiencing unexplained weight loss, it's important to discuss this with your healthcare provider as early diagnosis and proper treatment may help slow disease progression.
October 14, 2025