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Santa Monica, CA
December 25, 2025
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Can amyloidosis affect bone?

Yes, amyloidosis can affect bones, though this is more common with certain types. Dialysis-related amyloidosis typically affects the joints, tendons, and bones. This form of amyloidosis develops in people who have been on long-term dialysis treatment.

While AL amyloidosis (the most common Show Full Answer

Can amyloidosis affect bone?

Yes, amyloidosis can affect bones, though this is more common with certain types. Dialysis-related amyloidosis typically affects the joints, tendons, and bones. This form of amyloidosis develops in people who have been on long-term dialysis treatment.

While AL amyloidosis (the most common type) primarily affects organs like the heart and kidneys, it can also cause swelling in joints when amyloid deposits collect in the joint lining. This can lead to pain in various areas including the shoulders, lower back, and other joints.

The bone marrow itself is where AL amyloidosis begins. Abnormal plasma cells in the bone marrow start producing faulty proteins that form amyloid deposits throughout the body.

If you're experiencing bone or joint-related symptoms, it's important to discuss them with your healthcare provider so they can determine if they're related to amyloidosis and recommend appropriate management strategies.

December 25, 2025

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