What symptoms can you expect as amyloidosis progresses?
As amyloidosis advances, symptoms typically worsen as amyloid protein deposits build up in various organs. The specific symptoms depend on which organs are affected, but here's what you might experience:
Heart-Related Symptoms
* Shortness of breath
* Irregular Show Full Answer
What symptoms can you expect as amyloidosis progresses?
As amyloidosis advances, symptoms typically worsen as amyloid protein deposits build up in various organs. The specific symptoms depend on which organs are affected, but here's what you might experience:
Heart-Related Symptoms:
* Shortness of breath
* Irregular heartbeats (arrhythmias)
* Dizziness or lightheadedness
* Swelling in ankles, legs, and abdomen from fluid buildup
* Reduced ability to exercise or do daily activities
The heart walls become stiff and can't pump blood efficiently, which can eventually lead to heart failure.
Nervous System Symptoms:
* Tingling, burning, or pins-and-needles sensations (usually starting in the feet)
* Numbness in hands and feet
* Muscle weakness
* Problems with balance and coordination
* Carpal tunnel syndrome
* Pain or abnormal sensations
Digestive System Symptoms:
* Nausea and vomiting
* Constipation or diarrhea
* Weight loss
* Loss of appetite
* Acid reflux
Blood Pressure Issues:
* Drop in blood pressure when standing up (orthostatic hypotension)
* Feeling faint or dizzy when changing positions
Other Symptoms:
* Enlarged tongue that may look rippled at the edges
* Difficulty swallowing
* Easy bruising
* Kidney problems
* Swelling in soft tissues
The disease often progresses quickly, and symptoms become more severe as organ function declines. Regular monitoring with your healthcare team is important to track progression and adjust treatment.
January 28