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A MyAmyloidosisTeam Member asked a question 💭
New Orleans, LA
January 29
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Does hATTR amyloidosis affect the brain?

hATTR amyloidosis primarily affects the nerves, heart, and digestive system rather than the brain itself. The condition causes abnormal protein deposits to build up in these areas, leading to symptoms like:

- Numbness, tingling, or weakness in the hands and feet (nerve damage)
- Show Full Answer

Does hATTR amyloidosis affect the brain?

hATTR amyloidosis primarily affects the nerves, heart, and digestive system rather than the brain itself. The condition causes abnormal protein deposits to build up in these areas, leading to symptoms like:

- Numbness, tingling, or weakness in the hands and feet (nerve damage)
- Heart problems including shortness of breath and irregular heartbeat
- Digestive issues like diarrhea or constipation
- Problems with blood pressure control

While hATTR amyloidosis significantly impacts the nervous system, this typically refers to the peripheral nerves (those outside the brain and spinal cord) and the autonomic nervous system (which controls automatic body functions). The brain is not commonly mentioned as a primary site of amyloid deposits in hATTR amyloidosis.

If you're experiencing neurological symptoms or have concerns about how hATTR might be affecting your nervous system, it's important to discuss these with your healthcare team. They can help determine which symptoms are related to your condition and adjust your treatment plan accordingly.

January 29

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