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Real members of MyAmyloidosisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
February 4
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Can cardiac amyloidosis affect your knees and worsen knee pain?

Yes, amyloidosis can affect your knees, though joint pain is a rare symptom. When it does occur, it's most commonly associated with AL amyloidosis (amyloid light-chain amyloidosis).

Amyloid proteins can build up in several areas around your joints:

* The Show Full Answer

Can cardiac amyloidosis affect your knees and worsen knee pain?

Yes, amyloidosis can affect your knees, though joint pain is a rare symptom. When it does occur, it's most commonly associated with AL amyloidosis (amyloid light-chain amyloidosis).

Amyloid proteins can build up in several areas around your joints:

* The synovial membranes (tissues that cushion and lubricate joints)
* Cartilage or tendons around the joints
* On and in the bones themselves near joints

This buildup can cause joint stiffness, swelling, weakness, and pain. When amyloid deposits occur near bones and joints, the pain might feel similar to or worsen existing joint problems like your bone-on-bone knee condition.

It's important to let your health care team know about your worsening knee pain. They can determine whether amyloidosis is contributing to your symptoms or if other factors are involved. Joint pain from amyloidosis can sometimes be confused with other joint conditions, so proper evaluation is essential.

A MyAmyloidosisTeam member noted that amyloid buildup can occur throughout the body or in specific joints, which could explain why both of your knees are affected.

February 4

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Saint Louis, MO