How is wild-type amyloidosis affecting the heart treated?
Wild-type amyloidosis primarily affects the heart, so treatment focuses on slowing disease progression and managing symptoms. A cardiologist typically leads your care.
Medications to Control Amyloidosis:
Several FDA-approved medications help stabilize the Show Full Answer
How is wild-type amyloidosis affecting the heart treated?
Wild-type amyloidosis primarily affects the heart, so treatment focuses on slowing disease progression and managing symptoms. A cardiologist typically leads your care.
Medications to Control Amyloidosis:
Several FDA-approved medications help stabilize the transthyretin protein, preventing it from misfolding and reducing amyloid buildup in the heart:
* Acoramidis (Attruby)
* Tafamidis (Vyndamax)
* Tafamidis meglumine (Vyndaqel)
* Vutrisiran
These TTR stabilizers help keep the protein in its correct shape. Another option is diflunisal, an NSAID sometimes used off-label to stop amyloid formation.
Important Note About Heart Medications:
Many standard heart medications like beta-blockers, calcium channel blockers, and ACE inhibitors can actually cause additional harm in wild-type amyloidosis. They may lower blood pressure too much or not work well with a stiffened heart muscle.
Heart Transplant:
For severe cases with lasting heart damage, a heart transplant may be recommended. However, since wild-type amyloidosis typically affects older adults, many people may not be eligible for this major surgery due to age or other health conditions.
The good news is that wild-type amyloidosis develops slowly, and new treatments are helping people live longer, healthier lives with better quality of life.
February 5
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