Does amyloidosis affect fingernails or toenails?
Yes, amyloidosis can affect both fingernails and toenails, though nail changes are somewhat rare. This happens most often with systemic AL amyloidosis, where amyloid proteins build up in multiple areas of your body.
Nail changes you might notice include:
* Thin or brittle Show Full Answer
Does amyloidosis affect fingernails or toenails?
Yes, amyloidosis can affect both fingernails and toenails, though nail changes are somewhat rare. This happens most often with systemic AL amyloidosis, where amyloid proteins build up in multiple areas of your body.
Nail changes you might notice include:
* Thin or brittle nails that break easily
* Ridges or grooves running along the length of the nails
* Rough texture
* Split nails
* Brown spots or discoloration
* Onycholysis (nails separating from the nail bed)
* Easy bruising or blood under the nails
In some cases, nail changes may be one of the earliest visible signs of amyloidosis. Cases have been reported of people developing onycholysis with slow-growing nodules under the toenail bed.
If you're receiving chemotherapy for AL amyloidosis, you might also experience nail-related side effects like damage to the cuticles or nail lifting.
It's important to talk with your doctor about any nail changes you notice. While they may be related to amyloidosis, they could also signal an infection or other condition that needs attention. If your nails are painful, have an unusual odor, or changes happen suddenly, reach out to your healthcare provider.
March 4
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