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March 10
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A MyAmyloidosisTeam Member

I would suggest that you see your Neurologist who will likely recommend an MRI. Spinal stenosis is a common symptom.

I was diagnosed with HATTR in June of 2023. I was diagnosed with Spinal Stenosis in that Fall after an MRI, not necessarily caused by HATTR, but after a year of physical therapy, I finally opted for lumbar fusion. All 4 samples from the surgery came back positive for Amyloidosis.

Doing much better after surgery, but your treatment is personal decision that you want to make after being fully informed of what you are dealing with. Hopefully, your issues are more easily treatable.

March 26
A MyAmyloidosisTeam Member

Thank you Joe for your response.
My neurologist told me that it is one of the affects of hATTR. It showed up on an earlier MRI-3 years ago and I’m scheduled to take another MRI. He wanted to immediately refer me to a surgeon. I want to wait until after these new results. I have heard how many felt better after surgery. I saw my mother improve after the surgery—however she was not diagnosed for the disease at that time. She was diagnosed 3 years later because her heart stopped and she was taken to shock trama. The doctors found the disease while she was in ICU. That occurred in 2019 and she passed away on 2020.

May 3
MyAmyloidosisTeam

Have you experienced lower back pain or sciatica with hATTR cardiac or polyneuropathy amyloidosis? What was the treatment for relief?

Lower back pain and sciatica can occur with hATTR polyneuropathy as nerve damage spreads throughout the body. While the search results don't specifically mention lower back pain or sciatica Show Full Answer

Have you experienced lower back pain or sciatica with hATTR cardiac or polyneuropathy amyloidosis? What was the treatment for relief?

Lower back pain and sciatica can occur with hATTR polyneuropathy as nerve damage spreads throughout the body. While the search results don't specifically mention lower back pain or sciatica, they do describe how hATTR-PN causes widespread nerve symptoms.

Nerve symptoms in hATTR polyneuropathy often start in the toes and gradually spread upward through the legs, and can eventually affect other areas. People commonly experience shooting pain, numbness, tingling, and burning sensations in their limbs.

Treatment approaches for nerve pain relief include:

- Medications specifically for neuropathic pain management
- Disease-modifying therapies that slow or halt hATTR progression
- Physical therapy to maintain muscle strength and mobility
- Symptom management for autonomic nervous system issues

It's important to discuss your specific pain symptoms with your healthcare team. They can determine if your lower back pain or sciatica is related to your hATTR and recommend appropriate treatments tailored to your situation.

March 10

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California City, CA