What causes loss of leg strength in amyloidosis?
Loss of leg strength is a common symptom in amyloidosis and can happen for several reasons:
Nerve damage (neuropathy): When amyloid proteins build up around motor nerves, they can cause muscle weakness and loss of function in your legs and feet. This damage tends to worsen Show Full Answer
What causes loss of leg strength in amyloidosis?
Loss of leg strength is a common symptom in amyloidosis and can happen for several reasons:
Nerve damage (neuropathy): When amyloid proteins build up around motor nerves, they can cause muscle weakness and loss of function in your legs and feet. This damage tends to worsen the longer you live with the condition.
Muscle loss: Amyloid deposits can lead to muscle wasting, which adds to the weakness you feel in your legs. This can be tied to reduced activity, nutrition changes, and the overall energy cost of living with a chronic condition.
Fatigue: The deep, ongoing tiredness from amyloidosis can make your muscles work less efficiently, making it harder to walk, stand, or perform daily activities.
You might notice:
- Trouble walking or changes in your gait
- Back, hip, knee, or leg pain
- Difficulty with balance
- Increased risk of falling
- Loss of stamina during activities
If you're experiencing significant leg weakness or muscle loss, talk to your doctor. They may recommend working with a physical therapist or occupational therapist to help slow muscle loss and preserve your independence.
March 19
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