That's a really understandable concern — belly swelling can be uncomfortable and frustrating to deal with. However, the abdominal swelling associated with ATTR-CM is typically caused by fluid buildup (edema), not fat tissue. This means weight-loss injections or cosmetic fat-removal procedures wouldn't address the root Show Full Answer
That's a really understandable concern — belly swelling can be uncomfortable and frustrating to deal with. However, the abdominal swelling associated with ATTR-CM is typically caused by fluid buildup (edema), not fat tissue. This means weight-loss injections or cosmetic fat-removal procedures wouldn't address the root cause.
The most effective approach is to treat the underlying ATTR-CM itself. There are three FDA-approved medications that can slow the disease:
- Tafamidis (Vyndamax) — taken orally
- Acoramidis (Attruby) — taken orally
- Vutrisiran (Amvuttra) — an injection given every three months
These medications work by either stabilizing the TTR protein or reducing how much of it the liver produces, which helps slow the buildup of amyloid in the body. In addition to ATTR-CM treatments, doctors often prescribe diuretics to help flush out excess fluid, which can reduce swelling in the belly, legs, and ankles. One MyAmyloidosisTeam member shared that a diuretic helped manage their swelling effectively.
It's really important to speak with a cardiologist about the best treatment plan. Addressing the fluid buildup through proper medical care is the safest and most effective path forward.
June 8
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