That's a really valid concern. With wild-type ATTR, abnormal TTR protein can build up in tendons, making them weaker and more prone to rupture — particularly the biceps tendon in the upper arm. Roughly 1 in 3 people with wild-type ATTR experience this, so you're right that it's a significant risk.
While there's no Show Full Answer
That's a really valid concern. With wild-type ATTR, abnormal TTR protein can build up in tendons, making them weaker and more prone to rupture — particularly the biceps tendon in the upper arm. Roughly 1 in 3 people with wild-type ATTR experience this, so you're right that it's a significant risk.
While there's no guaranteed way to prevent it entirely, there are some sensible steps that may help reduce the risk:
- Avoid heavy lifting or sudden forceful movements that put strain on tendons
- Work with a physical therapist to build safe, low-impact strength and mobility routines
- Stay on your prescribed ATTR treatment, as reducing TTR buildup throughout the body may help protect tendons over time
- Report any tendon pain or weakness early to your doctor — catching issues early matters
It's also worth having an open conversation with your healthcare team about your specific risk level and any activity modifications they'd recommend for your situation.
June 29
Join
Your Privacy Choices
