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Real members of MyAmyloidosisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
August 27
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MyAmyloidosisTeam

That sounds really uncomfortable, and it makes sense to want answers. With wild-type ATTR amyloidosis, amyloid deposits don't just stay in one place — they can build up in nerves throughout the body, not only in the wrists.

The itching and tingling in your back is likely related to peripheral neuropathy, which is nerve Show Full Answer

That sounds really uncomfortable, and it makes sense to want answers. With wild-type ATTR amyloidosis, amyloid deposits don't just stay in one place — they can build up in nerves throughout the body, not only in the wrists.

The itching and tingling in your back is likely related to peripheral neuropathy, which is nerve damage caused by amyloid deposits affecting the nerves outside the brain and spinal cord. When these sensory nerves are irritated or compressed, they can send confusing signals — like tingling, burning, or itching — even when nothing is physically touching the skin. As ATTR amyloidosis progresses, these nerve symptoms can spread or intensify. Common nerve-related sensations people experience include:

- Tingling or "pins and needles"
- Burning sensations
- Itching
- Numbness
- Sensitivity to touch

It's really important to let your doctor know about these new back symptoms as soon as possible. Tracking when it happens, how long it lasts, and what makes it better or worse can be very helpful information to bring to your appointment.

August 27

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