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Real members of MyAmyloidosisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
October 1, 2025
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A MyAmyloidosisTeam Member

I take gabapentin and it helps

October 1, 2025
A MyAmyloidosisTeam Member

Neuropathy in AL patients can be caused by the disease itself OR by some of the treatment drugs used to treat it. Velcade is the drug used most commonly used now that can cause neuropathy. Thalidomide, which is not commonly used any longer is most definately know to cause neuropathy. It is extremely important to notify your doctor of any neuropathy symptoms that occur if you are currently receiving treatments. They may stop that particular drug or watch your symptoms more closely to make sure they dont advance. If the neuropathy is caused by the treatment drugs, it may get better once treatment stops. Any neuropathy that remains a year or so later may be permanent. Talk to your doctor to try and determine the cause of your neuropathy. Gabapentin, cymbalta and lyrica are some of the most common treatments to help ease the pain associated with neuropathy.

October 8, 2025
A MyAmyloidosisTeam Member

My husband takes lyrica, gabapentin did not help.

October 8, 2025 (edited)
MyAmyloidosisTeam

Several medications used to treat AL amyloidosis can help manage the condition and its symptoms. The most common treatments include chemotherapy drugs and targeted therapies that work by attacking the abnormal plasma cells that cause AL amyloidosis.

Common medications that have shown effectiveness include
• Alkeran Show Full Answer

Several medications used to treat AL amyloidosis can help manage the condition and its symptoms. The most common treatments include chemotherapy drugs and targeted therapies that work by attacking the abnormal plasma cells that cause AL amyloidosis.

Common medications that have shown effectiveness include:
• Alkeran (melphalan)
• Cytoxan (cyclophosphamide)
• Velcade (bortezomib)
• Darzalex (daratumumab)
• Thalomid (thalidomide)
• Revlimid (lenalidomide) While these medications aren't a cure, they can help slow disease progression and potentially lead to remission. Studies have shown promising results - for example, some patients have achieved complete remission using combinations of these drugs. It's important to discuss specific treatment options with your healthcare provider, as they can develop a personalized plan based on your symptoms and condition severity.

October 1, 2025

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