What tests are used to evaluate wild-type ATTR amyloidosis for staging?
For wild-type ATTR amyloidosis (wt-ATTR), doctors use cardiac biomarkers to stage the disease and assess heart damage. The staging focuses on how well your heart is functioning.
The key biomarkers tested include:
* NT-proBNP (N-terminal pro-brain Show Full Answer
What tests are used to evaluate wild-type ATTR amyloidosis for staging?
For wild-type ATTR amyloidosis (wt-ATTR), doctors use cardiac biomarkers to stage the disease and assess heart damage. The staging focuses on how well your heart is functioning.
The key biomarkers tested include:
* NT-proBNP (N-terminal pro-brain natriuretic peptide) - Shows when the heart is under stress or not pumping well
* Cardiac troponin (cTnT or cTnI) - Indicates damage to heart muscle cells
These blood tests help doctors determine your stage by comparing your results to specific cutoff levels. The staging system helps guide treatment decisions and provides information about prognosis.
Additional tests that may be ordered include echocardiograms to visualize heart function and structure, along with other cardiac imaging studies to assess the extent of amyloid deposits in the heart.
October 26, 2025