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Real members of MyAmyloidosisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

I have a question about Vyndamax..is this the same as ammuttra

A MyAmyloidosisTeam Member asked a question 💭
April 7
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A MyAmyloidosisTeam Member

85 is great. The scientists working so hard like they have in the past 6 years may develope a cure and i make it to 85. They have accomplisheda great deal in a short time so there's hope.

April 8
A MyAmyloidosisTeam Member

Hi I’m Gary Marsden and I currently am on both Amvuttra and Attruby (acoramidis)). Amvuttra is by injection every 3 months, and Attruby 320mg.2 caps twice daily. I believe I’m in the later stages as my breathing problems began inn 2017 but I wasn’t diagnosed until 2024 with ATTR-CM. Began taking Vyndaqel in January 2025 and switched to ATTruby in January 2026. The Amvuttra began on October 31 2025 and am due for my 3rd. Injection at the end of April. All in all I think I’m doing quite well. I do get shortness of breath these days and my Arthritis flares up often, don’t know if that might be due to the condition , or maybe a side-effect of the meds, but I am 85 years old and there’s that, eh!
Gary

April 8
MyAmyloidosisTeam

Are Vyndamax and Amvuttra the same medication?

No, Vyndamax and Amvuttra are not the same medication. They are two different treatments for amyloidosis that work in different ways.

Amvuttra is an RNA interference (RNAi) therapy that works by blocking the production of abnormal transthyretin (TTR) protein before it can Show Full Answer

Are Vyndamax and Amvuttra the same medication?

No, Vyndamax and Amvuttra are not the same medication. They are two different treatments for amyloidosis that work in different ways.

Amvuttra is an RNA interference (RNAi) therapy that works by blocking the production of abnormal transthyretin (TTR) protein before it can build up and cause harm. It's given as a subcutaneous injection (a shot under the skin) once every three months.

Vyndamax, on the other hand, is a TTR stabilizer that works differently. Instead of stopping protein production, it helps stabilize the TTR protein to prevent it from breaking apart and forming amyloid deposits.

The two medications have different administration methods, dosing schedules, and mechanisms of action. Your healthcare team can help determine which treatment option is most appropriate for your specific type of amyloidosis and individual circumstances.

April 7

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