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Real members of MyAmyloidosisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyAmyloidosisTeam Member asked a question 💭
Venice, FL

Can vyndamax cause AFIB?

September 7
 · 
Reactions
A MyAmyloidosisTeam Member

Thanks Gary

September 10
A MyAmyloidosisTeam Member

Hi Janice, For what it’s worth I was diagnosed with AFIB a few years before Amyloidosis and never did take Vindamax>. Gary

September 10
A MyAmyloidosisTeam Member

See above

September 7
MyAmyloidosisTeam

That's a really important question. Vyndamax (tafamidis) itself is not known to directly cause AFib. However, AFib is a common complication of cardiac amyloidosis itself, due to the way amyloid deposits affect the heart's electrical system.

Here's what's worth knowing:

- AFib is frequently seen in people with cardiac Show Full Answer

That's a really important question. Vyndamax (tafamidis) itself is not known to directly cause AFib. However, AFib is a common complication of cardiac amyloidosis itself, due to the way amyloid deposits affect the heart's electrical system.

Here's what's worth knowing:

- AFib is frequently seen in people with cardiac amyloidosis as the disease progresses
- Vyndamax works by stabilizing the TTR protein to slow further amyloid buildup — it doesn't remove deposits already in the heart
- Existing deposits can continue to affect heart rhythm even while on treatment

One important note: having AFib alongside cardiac amyloidosis can affect eligibility for certain other treatments or devices, so it's worth discussing with your cardiologist.

If you're noticing any irregular heartbeat or new symptoms while on Vyndamax, it's best to reach out to your doctor promptly. Also, be aware that allergic reactions to Vyndamax are possible — seek immediate medical attention if you experience trouble swallowing, hives, chest tightness, or a fast heartbeat.

September 7

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