I have attr Cardiac Amyloidosis. I get both Vyndamax and Amutra.
June 2
AFib (atrial fibrillation) is an irregular heart rhythm that can occur as a complication of ATTR-CM, where amyloid deposits affect the heart's electrical system. Managing it is typically handled alongside ATTR-CM treatment, and your cardiologist may recommend a pacemaker or defibrillator depending on how your heart's Show Full Answer
AFib (atrial fibrillation) is an irregular heart rhythm that can occur as a complication of ATTR-CM, where amyloid deposits affect the heart's electrical system. Managing it is typically handled alongside ATTR-CM treatment, and your cardiologist may recommend a pacemaker or defibrillator depending on how your heart's electrical system is affected. For ATTR-CM specifically, there are currently three FDA-approved medications. Here's a quick breakdown:
- Tafamidis (Vyndamax) — An oral pill that stabilizes the TTR protein to prevent further amyloid buildup
- Acoramidis (Attruby) — Also an oral pill that works in a similar way to tafamidis
- Vutrisiran (Amvuttra) — Given as an injection under the skin every three months
All three are considered strong options, and no single one is considered better than the others. The best choice really depends on your individual situation, so it's worth having a detailed conversation with your care team.
Early treatment is key — research shows that starting treatment sooner leads to better outcomes over time. More options are also currently being studied in clinical trials, so the landscape continues to improve.
May 31
I have a ICD. Would Vyndamax directly impact AFib?
May 31
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