There are actually quite a few more than two drugs used to treat amyloidosis β the treatment options depend on the type of amyloidosis. Here's a summary of the main categories and examples:
For AL Amyloidosis
- Chemotherapy β melphalan (Alkeran/Evomela), cyclophosphamide (Cytoxan), lenalidomide (Revlimid), pomalidomide Show Full Answer
There are actually quite a few more than two drugs used to treat amyloidosis β the treatment options depend on the type of amyloidosis. Here's a summary of the main categories and examples:
For AL Amyloidosis:
- Chemotherapy β melphalan (Alkeran/Evomela), cyclophosphamide (Cytoxan), lenalidomide (Revlimid), pomalidomide (Pomalyst)
- Proteasome Inhibitors β bortezomib (Velcade), carfilzomib (Kyprolis), ixazomib (Ninlaro)
- Monoclonal Antibodies β daratumumab (Darzalex), daratumumab + hyaluronidase (Darzalex Faspro)
- Immunomodulatory Drugs β thalidomide (Thalomid), lenalidomide (Revlimid)
- Steroids β dexamethasone, prednisone (used alongside other drugs)
For ATTR Amyloidosis:
- Tafamidis (Vyndamax/Vyndaqel) β stabilizes the TTR protein to prevent amyloid formation
- Diflunisal (Dolobid) β may help slow amyloid buildup
Most treatments are given in combination rather than as a single drug. It's always best to speak with your care team about which options are right for your specific type and stage.
August 31