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A MyAmyloidosisTeam Member asked a question πŸ’­
August 31
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There are actually quite a few more than two drugs used to treat amyloidosis β€” the treatment options depend on the type of amyloidosis. Here's a summary of the main categories and examples:

For AL Amyloidosis
- Chemotherapy – melphalan (Alkeran/Evomela), cyclophosphamide (Cytoxan), lenalidomide (Revlimid), pomalidomide Show Full Answer

There are actually quite a few more than two drugs used to treat amyloidosis β€” the treatment options depend on the type of amyloidosis. Here's a summary of the main categories and examples:

For AL Amyloidosis:
- Chemotherapy – melphalan (Alkeran/Evomela), cyclophosphamide (Cytoxan), lenalidomide (Revlimid), pomalidomide (Pomalyst)
- Proteasome Inhibitors – bortezomib (Velcade), carfilzomib (Kyprolis), ixazomib (Ninlaro)
- Monoclonal Antibodies – daratumumab (Darzalex), daratumumab + hyaluronidase (Darzalex Faspro)
- Immunomodulatory Drugs – thalidomide (Thalomid), lenalidomide (Revlimid)
- Steroids – dexamethasone, prednisone (used alongside other drugs)

For ATTR Amyloidosis:
- Tafamidis (Vyndamax/Vyndaqel) – stabilizes the TTR protein to prevent amyloid formation
- Diflunisal (Dolobid) – may help slow amyloid buildup

Most treatments are given in combination rather than as a single drug. It's always best to speak with your care team about which options are right for your specific type and stage.

August 31

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