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Real members of MyAmyloidosisTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
October 13
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A MyAmyloidosisTeam Member

The drug is nucresiran, a silencer. It is also known as the trition cm study. It is a double blind placebo controlled study with a 66% chance that you receive the drug. The placebo is normal saline.

October 13
MyAmyloidosisTeam

Great question! It sounds like you may be referring to a clinical trial involving a medication — possibly one being studied for amyloidosis. The name "nucreserine" doesn't closely match any currently known amyloidosis treatments or trials in available information, so it's worth double-checking the exact spelling or name Show Full Answer

Great question! It sounds like you may be referring to a clinical trial involving a medication — possibly one being studied for amyloidosis. The name "nucreserine" doesn't closely match any currently known amyloidosis treatments or trials in available information, so it's worth double-checking the exact spelling or name with your trial coordinator.

To answer your broader question about Attruby — yes, it is a stabilizer! Here's a quick breakdown:

- Attruby (acoramidis) is a TTR stabilizer, meaning it works by binding to the TTR protein and preventing it from breaking apart
- When TTR breaks apart, it forms harmful amyloid deposits that build up in the heart
- By keeping the protein stable, Attruby helps slow disease progression
- It is FDA-approved for ATTR cardiomyopathy (both wild-type and hereditary forms)
- It's taken as a tablet, twice daily

Since you're currently in a double-blind trial (meaning neither you nor your doctors know if you're getting the real drug or placebo), it's completely normal to be unsure what you're receiving — that's actually how these trials are designed to work to ensure unbiased results.

It would be worth asking your trial team whether the investigational drug you're on is a stabilizer or works differently, as they can share that general information without breaking the blind.

October 13

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